Konrad Kubiński

2023


Artykuł naukowy w czasopiśmie recenzowany


Wykonawca w realizowanym projekcie finansowanym przez NCN


2022


Artykuł naukowy w czasopiśmie recenzowany


Wykonawca w realizowanym projekcie finansowanym przez NCN


2021


Artykuł naukowy w czasopiśmie recenzowany


2020

  • Novel 1, 2, 4-Oxadiazole Derivatives in Drug Discovery
    [w:] Pharmaceuticals
  • Antifungal Agent 4-AN Changes the Genome-Wide Expression Profile, Downregulates Virulence-Associated Genes and Induces Necrosis in Candida albicans Cells
    [w:] MOLECULES

    • 2019

  • The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases
    [w:] MOLECULES
  • Novel steroid sulfatase inhibitors based on N‐thiophosphorylated 3‐(4‐aminophenyl)‐coumarin‐7‐O‐sulfamates
    [Novel steroid sulfatase inhibitors based on N‐thiophosphorylated 3‐(4‐aminophenyl)‐coumarin‐7‐O‐sulfamates ]
    [w:] DRUG DEVELOPMENT RESEARCH
  • New potent STS inhibitors based on fluorinated 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamates
    [w:] JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
  • Polysaccharide-Rich Fractions from Rosa rugosa Thunb.—Composition and Chemopreventive Potential
    [ Polysaccharide-Rich Fractions from Rosa rugosa Thunb.—Composition and Chemopreventive Potential]
    [w:] MOLECULES

    • 2018

  • Synthesis and antimicrobial activity of 4-substituted 1, 2, 3-triazole-coumarin derivatives
    [w:] MOLECULES
  • A representative of arylcyanomethylenequinone oximes effectively inhibits growth and formation of hyphae in Candida albicans and influences the activity of protein kinases in vitro
    [w:] SAUDI PHARMACEUTICAL JOURNAL
  • 1, 4-Naphthoquinone derivatives potently suppress Candida albicans growth, inhibit formation of hyphae and show no toxicity toward zebrafish embryos
    [w:] JOURNAL OF MEDICAL MICROBIOLOGY

    • 2017

  • Synthesis and biological evaluation of N‐acylated tyramine sulfamates containing C–F bonds as steroid sulfatase inhibitors
    [w:] Chemical Biology & Drug Design
  • Emodin, a natural inhibitor of protein kinase CK2, suppresses growth, hyphal development, and biofilm formation of Candida albicans
    [w:] YEAST
  • The Link between Protein Kinase CK2 and Atypical Kinase Rio1
    [w:] Pharmaceuticals
  • Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors
    [w:] EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
  • CX-4945: the protein kinase CK2 inhibitor and anti-cancer drug shows anti-fungal activity
    [w:] MOLECULAR AND CELLULAR BIOCHEMISTRY

    • 2016

  • Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1
    [w:] MOLECULAR AND CELLULAR BIOCHEMISTRY
  • Synthesis and Biological Evaluation of Fluorinated 3-Phenylcoumarin-7-O-Sulfamate Derivatives as Steroid Sulfatase Inhibitors
    [Synteza i biologiczna ewaluacja pochodnych Fluorinated 3-Phenylcoumarin-7-O-Sulfamate jako inhibitorów sulfatazy steroidowej]
    [w:] Chemical Biology & Drug Design
  • Synthesis and steroid sulfatase inhibitory activities of N-phosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates
    [Synteza i hamowanie aktywności sulfatazy steroidowej przez N-phosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates]
    [w:] MedChemComm
  • New family of antimicrobial agents derived from 1,4-naphthoquinone
    [Nowa rodzina pochodnych 1,4-naftochinonu jako związki antybakteryjne]
    [w:] EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

    • Artykuł naukowy w wydawnictwie zbiorowym recenzowany


    2015


    Artykuł naukowy w czasopiśmie recenzowany


    2014

  • Human Protein Kinase CK2 Phosphorylates Matrix Metalloproteinase 2 and Inhibits its Activity
    [Ludzka kinaza białkowa CK2 fosforyluje MMP2 i hamuje jej aktywność]
    [w:] CHEMBIOCHEM
  • AD-O53.2 - nowe rekombinowane białko fuzyjne o aktywności TRAIL/Apo2L i Smac/Diablo przezwycięża oporność ludzkich komórek rakowych na TRAIL/Apo2L
    [w:] INVESTIGATIONAL NEW DRUGS

    • 2010

  • Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits
    [Fosforylacja syntazy tymidylanowej z różnych źródeł przez ludzką kinazę CK2 i jej podjednostki katalityczne]
    [w:] BIOORGANIC CHEMISTRY

    • 2008

  • Drożdżowy czynnik Svf1 jako nowy patner interakcji, regulator i substrat in vitro kinazy białkowej CK2
    [w:] MOLECULAR AND CELLULAR BIOCHEMISTRY
  • Catalytic activity of mutants of yeast protein kinase CK2alpha
    [Aktywność katalityczna mutantów drożdżowej kinazy białkowej CK2alfa]
    [w:] ACTA BIOCHIMICA POLONICA

    • 2007

  • Yeast holoenzyme of protein kinase CK2 requires both beta and beta' regulatory subunits for its activity
    [Holoenzym drożdżowej kinazy białkowej CK2 wymaga do swojej aktywności dwóch podjednostek regulatorowych ]
    [w:] MOLECULAR AND CELLULAR BIOCHEMISTRY