Laboratory of Oxidative Stress

Department of Biomedicine and Environmental Research
Konstantynow Ave 1J, 20-708 Lublin

Phone:  +48 81 45 45 615

 

Education

• M.Sc. in biology: 1994, Faculty of Biology and Earth Sciences (at present Faculty of Biology and Biotechnology), Maria Curie-Skłodowska University, Lublin, Poland
• Ph.D. in biology: 1999, Faculty of Biology and Earth Sciences (at present Faculty of Biology and Biotechnology), Maria Curie-Skłodowska University, Lublin, Poland
• Post-doctoral degree in biology: 2016, Faculty of Biology and Chemistry, University of Bialystok, Poland
• 2004/2005: Two-Semestral Postgraduate Studies in the range of knowledge about laboratory animals at the Faculty of Animal Science, Warsaw University of Life Sciences, Poland

List of publications

1. Author / co-author of 50 scientific papers 

• 34 articles published in journals included in the A list of Ministry of Science and Higher Education
• 1 scientific article published in a journal included in the B list of Ministry of Science and Higher Education
• 9 chapters in monographs (including two chapters in a book published by John Wiley & Sons)
• 2 scientific articles published in Acta Polon. Toxicol.
• 2 scientific-popular articles
• 2 scientific-popular brochures
• h-index 15 (Scopus)

2. Author / co-author of 68 conference announcements

3. Co-author of Editorials of the Special Issues for:

• Oxidative Medicine and Cellular Longevity [IF_2017-2018: 4.936] 
• Biology [IF_5-yr: 4.4] 

Selected papers

in journals covered by Journal Citation Reports (JCR) [2005-2023]

• Ścibior A., Aureliano M., Holder A.A., Llopis J. 2023. Metals and Metal Complexes in Diseases with a Focus on COVID-19: Facts and Opinions, Biology, 12(6), 868 [IF_5-yr – 4.4]
• Ścibior A., Llopis J., Dobrakowski P.P., Męcik-Kronenberg T. CNS-related effects caused by vanadium at realistic exposure levels in humans: a comprehensive overview supplemented with selected animal studies. 2023. Int. J. Mol. Sci., Special Issue: "Advances in Metal Complexes: Pharmacological Activity", 21, 9004 [IF_5-yr – 6.2]
• Ścibior A. 2022. Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline. Antioxidants, 11, 790 [IF_5-yr – 7.3]
• Ścibior A., Wnuk E. 2022. Elements and COVID-19: A comprehensive overview of studies on their blood/urinary levels and supplementation with an update on clinical trials. Biology, Special Issue: "Metals and Metal Complexes in Diseases with a focus on COVID-19: Facts and Opinions", 11, 215 [IF_5-yr – 4.4]
• Ścibior A., Wojda I., Wnuk E., Pietrzyk Ł., Plewa Z. 2021. "Response of cytoprotective and detoxifying proteins to vanadate and/or magnesium in the rat liver: the Nrf2- Keap1 system", Oxid. Med. Cell. Longev., 2021, 8447456 [IF₂₀₂₂ – 7.310]
• Klich D., Łopucki R., Gałązka M., Ścibior A., Gołębiowska D., Brzezińska R., Kruszewski B., Kaleta T., Olech W. 2021. Stress hormone level and the welfare of captive European bison (Bison bonasus): the effects of visitor pressure and the social structure of herds. Acta Vet. Scand., 63:24 [IF_2022-23 – 2.048]
• Ścibior A., Wnuk E., Gołębiowska D. 2021. Wild animals in studies on vanadium bioaccumulation - Potential animal models of environmental vanadium contamination: A comprehensive overview with a Polish accent. Sci. Total Environ., 785, 147205 [IF_2022-23 – 10.754]
• Ścibior A., Hus I., Mańko J., Jawniak D. 2020. Evaluation of the level of selected iron-related proteins/receptors in the liver of rats during separate/combined vanadium and magnesium administration, J. Trace Elem. Med. Biol., 61, 126550 [IF₂₀₂₀ – 3.53]
• Ścibior A., Pietrzyk Ł., Plewa Z., Skiba A. 2020. Vanadium: risks and possible benefits in the light of a comprehensive overview of its pharmacotoxicological mechanisms and multi-applications with a summary of further research trends, J. Trace Elem. Med. Biol., 61: 126508 [IF₂₀₂₀ – 3.53]
• Ścibior A., Szychowski KA., Zwolak I., Dachowska K., Gmiński J. 2020. In vitro effect of vanadyl sulfate on cultured primary astrocytes: cell viability and oxidative stress markers, J. Appl. Toxicol., 40(6): 737-747 [IF₂₀₂₀ – 3.446]
• Ścibior A., Kurus J. 2019. Vanadium and oxidative stress markers - in vivo model: a review. Curr. Med. Chem., 26: 5456-5500 [IF_5-yr – 5.046]
• Klich D., Łopucki R., Ścibior A., Gołębiowska D., Wojciechowska M. 2020. Roe deer stress response to a wind farms: Methodological and practical implications. Ecol. Ind., 117, 106658 [IF_2022-23 – 6.263]
• Łopucki R.,  Klich D., Ścibior A., Gołębiowska D. 2019. Hormonal adjustments to urban conditions: stress hormone levels in urban and rural populations of Apodemus agrarius. Urban Ecosys., 22: 435-442 [IF_2022-23: 2.686]
• Ścibior A., Adamczyk A., Gołębiowska D., Kurus J. 2018. Evaluation of lipid peroxidation and the level of some elements in rat erythrocytes during separate and combined vanadium and magnesium administration. Chem. Biol. Int., 293: 1-10 [IF₂₀₂₀ – 5.168]
• Ścibior A., Gołębiowska D., Adamczyk A., Kurus J., Staniszewska M., Sadok I. 2018. Evaluation of lipid peroxidation and antioxidant defense mechanisms in the bone of rats in conditions of separate and combined administration of vanadium (V) and magnesium (Mg). Chem. Biol. Int., 284: 112-125 [IF₂₀₂₀ – 5.168]
• Łopucki R., Klich D., Ścibior A., Gołębiowska D., Perzanowski K. 2018. Living in habitats affected by wind turbines may result in an increase in corticosterone levels in ground dwelling animals. Ecol. Ind., 84: 165-171 [IF_2022-23 – 6.263]
• Ścibior A. 2016. Vanadium (V) and magnesium (Mg) - In vivo interactions: A review. Chem. Biol. Int., 258: 214-233 [IF₂₀₂₀ – 5.192]
• Ścibior A., Llopis J., Holder A.A., Altamirano-Lozano M. 2016. Vanadium Toxicological Potential versus Its Pharmacological Activity: New Developments and Research. Oxid. Med. Cell. Longev., vol. 2016: 7612347 [IF₂₀₁₆ – 4.593]
• Ścibior A., Adamczyk A., Mroczka, R., Niedźwiecka I., Gołębiowska D., Fornal E. 2014. Effects of vanadium (V) and magnesium (Mg) on rat bone tissue: bone mineral status and micromorphology. Consequences of V-Mg interactions. Metallomics, 6: 2260-2278 [IF_5-yr – 4.176]
• Ścibior A., Adamczyk A., Gołębiowska D., Niedźwiecka I., Fornal E. 2014. The influence of combined magnesium and vanadate administration on the level of some elements in rats' tissues: V-Mg interactions and the role of iron essential protein DMT-1 in the mechanism underlying altered tissues iron level. Metallomics, 6: 907-920 [IF_5-yr - 4.176]
• Ścibior A., Gołębiowska D., Adamczyk A.,  Niedźwiecka I., Fornal E. 2014. The renal effects of vanadate exposure: potential biomarkers and oxidative stress as a mechanism of functional renal disorders - preliminary studies. BioMed Res. Int., Special Issue: Prooxidant Mechanisms in Toxicology (POMT), vol. 2014, 1-15 [IF₂₀₂₀ - 3.411]
• Ścibior A., Gołębiowska D.,  Niedźwiecka I., 2013. Magnesium can protect against vanadium-induced lipid peroxidation in the hepatic tissue. Oxid. Med. Cell. Longev., Special Issue: Lipid Peroxidation Products in Human Health and Disease (LPPHHD), vol. 2013, 1-11 [IF₂₀₂₂ – 7.310]
• Ścibior A., Gołębiowska D., Niedźwiecka I., Adamczyk A. 2013. Inhibitory and stimulating effect of magnesium on vanadate-induced lipid peroxidation under in vitro conditions. Indian J. Exp. Biol., 51: 721-731 [IF₂₀₂₁ - 0.944]
• Ścibior A., Adamczyk A., Gołębiowska D., Niedźwiecka I., 2012. Effect of 12-week vanadate and magnesium co-administration on chosen haematological parameters as well as on some indices of iron and copper metabolism and biomarkers of oxidative stress in rats. Environ. Toxicol. Pharmacol., 34: 235-252 [IF_2022-23 – 5.785]
• Ścibior A., Zaporowska H. 2010. Effects of combined vanadate and magnesium treatment on erythrocyte antioxidant defence system in rats. Environ. Toxicol. Pharmacol., 30: 153-161 [IF_2022-23 – 5.785]
• Ścibior A., Zaporowska H., Niedźwiecka I., 2010. Lipid peroxidation in the kidney of rats treated with V and/or Mg in drinking water. J. Appl. Toxicol., 30: 487-496 [IF_2022-23 - 3.628]
• Ścibior A., Zaporowska H., Wolińska A., Ostrowski J. 2010. Antioxidant enzyme activity and lipid peroxidation in the blood of rats co-treated with vanadium (V⁺⁵) and chromium (Cr⁺³). Cell. Biol. Toxicol., 26: 509-526 [IF_2022-23 - 6.819]
• Ścibior A., Zaporowska H., Niedźwiecka I., 2009. Lipid peroxidation in the liver of rats treated with V and/or Mg in drinking water. J. Appl. Toxicol., 29: 619-628 [IF_2022-23 - 3.628]
• Ścibior A., Zaporowska H. 2009. Effects of combined treatment with vanadium(V) and chromium(III) on haematological parameters and plasma mineral status in rats. Trace Elem. Electroly., 26 (3): 104-113 [IF₂₀₂₃ - 0.492]
• Ścibior A., Zaporowska H. 2007. Effects of vanadium (V) and/or chromium (III) on L-ascorbic acid, glutathione as well as iron, zinc and copper levels in rat liver and kidney. J. Toxicol. Environ. Health, Part A, 70 (8): 696-704 [IF_2022-23 - 3.24]
• Ścibior A., Zaporowska H, Ostrowski J., Banach A. 2006. Combined effect of vanadium(V) and chromium(III) on lipid peroxidation in liver and kidney of rats. Chem. Biol. Int., 159 (3): 213-222 [IF₂₀₂₀ – 5.168]
• Ścibior A., Zaporowska H, Ostrowski J. 2006. Selected haematological and biochemical parameters of blood in rats after subchronic administration of vanadium and/or magnesium in drinking water. Arch. Environ. Contam. Toxicol., 51 (2): 287-295 [IF_2022-23 - 3.692]
• Ścibior A. 2005. Some selected blood parameters in rats exposed to vanadium and chromium via drinking water. Trace Elem. Electroly., 22 (1): 40-46 [IF₂₀₂₃ - 0.492]

Selected chapters in monographs

• Adamczyk A., Ścibior A. 2012. Determination of molybdenum in biological material by atomic absorption spectrometry using electrothermal atomization [published in Polish: Oznaczanie molibdenu w materiale biologicznym z zastosowaniem atomowej spektrometrii absorpcyjnej z atomizacją elektrotermiczną [in:] Science and industry - spectroscopic methods in practice, new challenges and prospects [monograph published in Polish: Nauka i przemysł: metody spektroskopowe w praktyce, nowe wyzwania i możliwości], (Ed.) Hubicki H., Publisher: UMCS, Lublin, ISBN: 978-83-77-84-086-3, pp. 210-213.
• Adamczyk A., Ścibior A., Gołębiowska D., Niedźwiecka I. 2012. Atomic absorption spectrometry in determination of selected elements in rats’ internal organs and physiological fluids [published in Polish: Zastosowanie atomowej spektrometrii absorpcyjnej do oznaczania wybranych pierwiastków w narządach wewnętrznych i płynach fizjologicznych szczurów [in:] Science and industry - spectroscopic methods in practice, new challenges and prospects [monograph published in Polish: Nauka i przemysł: metody spektroskopowe w praktyce, nowe wyzwania i możliwości], (Ed.) Hubicki H., Publisher: UMCS, Lublin, ISBN: 978-83-77-84-086-3, pp. 214-218.
• Ścibior A, Zaporowska H. 2002. Lipid peroxidation in selected internal organs of rats in the vanadium-zinc interaction [published in Polish: Peroksydacja lipidów w wybranych narządach wewnętrznych szczurów w interakcji wanad-cynk] [in:] Zinc in the Environment – Ecological and Methodological Problems [monograph published in Polish: Cynk w środowisku - problemy ekologiczne i metodyczne]. Scientific book of “Man and Environment” Committee at the Presidium of Polish Academy of Science, (Eds.) Kabata-Pendias A., Szteke B., ISBN: 83-902762-2-4, 33: 511-520.
• Ścibior A., Zaporowska H. 1998. Biochemical blood parameters of rats intoxicated with vanadium or/and selenium in drinking water [in:] Proceedings of the 2^nd International Conference entitled Trace Elements - Effects on Organisms and Environment, (Eds.) Migula P., Doleżych B., Nakonieczny M., Scientific-Technical Publisher EcoEdycja, Katowice, ISBN: 83-904174-6-4, pp. 199-203.

Chapters in a book "Vanadium in the Environment, Part 2: Health Effects"

Scientific-popular articles

• Ścibior A., Zaporowska H. 1997. Vanadium in the human environment [published in Polish: Wanad w środowisku człowieka], Ekopartner, 5 (67): 9-11

• Ścibior A., Zaporowska H. 1998. Selenium – dangerous and useful at once [published in Polish: Selen niebezpieczny i pożyteczny zarazem], Ekopartner, 11 (84): 10-11

Scientific-popular brochures

 

Special Issues

1. Lead Guest Editor of the Special Issue for Oxidative Medicine and Cellular Longevity [IF₂₀₂₂ 7.310] "Vanadium Toxicological Potential versus Its Pharmacological Activity: New Developments and Research"

http://www.hindawi.com/journals/omcl/si/145707/cfp/, http://www.hindawi.com/journals/omcl/si/145707/

• Prof. Mario Altamirano-Lozano, Facultad de Estudios Superiores Zaragoza, Mexico (Guest Editor)
• Prof. Alvin A. Holder, Old Dominion University, USA (Guest Editor)
• Prof. Juan Llopis, University of Granada, Spain (Guest Editor)

2. Guest Editor of the Special Issue for Biology [IF_5-yr 4.4] "Metals and Metal Complexes in Diseases with a focus on COVID-19: Facts and Opinions" https://www.mdpi.com/journal/biology/special_issues/metal_covid https://www.mdpi.com/2079-7737/12/6/868

The Special Issue is run in cooperation with:

• Prof. Manuel Aureliano, Universidade do Algarve, Portugal (Guest Editor)
• Prof. Alvin A. Holder, Old Dominion University, USA (Guest Editor)
• Prof. Juan Llopis, University of Granada, Spain (Guest Editor)

3. Guest Editor of the Special Issue for International Journal of Molecular Sciences [IF_5-yr 6.2] "Emerging Topics in Metal Complexes: Pharmacological Activity" https://www.mdpi.com/journal/ijms/special_issues/G300O371XX

The Special Issue is run in cooperation with:

• Prof. Manuel Aureliano, Universidade do Algarve, Portugal (Guest Editor)
• Prof. Juan Llopis, University of Granada, Spain (Guest Editor)

4. Guest Editor of the Special Issue for Toxics [IF_5-yr 4.8] "Recent Insights into Metal and Metal-Based Nanoparticle-Induced Cytotoxicity: Exposure, Effects and Mechanisms" 

https://www.mdpi.com/journal/toxics/special_issues/C1690UV868

The Special Issue is run in cooperation with:

• Prof. Manuel Aureliano, Universidade do Algarve, Portugal (Guest Editor)
• Prof. Juan Llopis, University of Granada, Spain (Guest Editor)

Participation in scientific conferences (some of them are listed below: 1996-2022)

• 7^th Scientific Conference "Animals in scientific research", Warsaw, Poland, 2022
• XVI International Magnesium Symposium "Magnesium in health and disease", Glasgow, 2022
• 6^th Scientific Conference "Animals in scientific research", Warsaw, Poland, 2019
• 22^nd Scientific Lublin Magnesium Conference: „Elements - from the environment to medicine”, Lublin, Poland, 2019
• 21^st Scientific Lublin Magnesium Conference: „Elements in the environment and medicine”, Lublin, Poland, 2018
• 12^th Training and Scientific Conference of the Polish Society of Toxicology: "Different faces of toxicology", Pulawy, Poland, 2017
• 5^th All-Polish Scientific Conference: "Animals in scientific research", Warsaw, Poland, 2017
• 19^th Scientific Lublin Magnesium Conference: „The significance of elements in the environment and medicine”, Lublin, Poland, 2016
• 5^th International Symposium on Metallomics, Beijing, China, 2015
• 18^th Scientific Lublin Magnesium Conference: „The role of elements in the biosphere”, Lublin, Poland, 2015
• 9^th International Vanadium Symposium: "Chemistry, Biological Chemistry & Toxicology", Padova, Italy, 2014
• 17^th Scientific Lublin Magnesium Conference: "Chemical Elements and the Quality of Life”, Lublin, Poland, 2014
• Scientific Conference of the Polish Society of Toxicology: "Human, Food, Environment – problems of modern toxicology”, Olsztyn, Poland, 2014

• 16^th Scientific Lublin Magnesium Conference: "Chemical Elements and Health”, Lublin, Poland, 2013

• 8^th International Vanadium Symposium: "Chemistry, Biological Chemistry & Toxicology, Washington DC, USA, 2012
• 11^th International Symposium: "Trace Elements in the Environment”, Olsztyn, Poland, 2012
• 14^th Meeting Toxicology and Environmental Health, Warsaw, Poland, 2009
• 10^th Symposium: "Trace Elements in the Environment”, Mielno, Poland, 2008
• 3^rd International Symposium FESTEM (Federation of European Societies on Trace Elements and Minerals), Santiago de Compostela, Spain, 2007
  

• 7^th International Scientific-Technical Conference: "Circulation of Elements in Nature: Bioaccumulation – Toxicity – Counteraction - European Integration”, Warsaw, Poland, 2007

• 5^th International Symposium: "Trace Elements in Human - New Perspectives”, Athens, Greece, 2005
  
• 6^th International Scientific-Technical Conference: "Circulation of Elements in Nature: Bioaccumulation – Toxicity – Counteraction - European Integration”, Warsaw, Poland, 2005

• 3^rd International Symposium: "Trace Elements and Minerals in Medicine and Biology”, Munich, Germany, 2004
• International Symposium: "Iron and Manganese in the Environment – Ecological and Methodological Problems”, Warsaw, Poland, 2004
• 7^th All-Polish Scientific Conference: "Xenobiotics Interactions”, Poznań, Poland, 2004

• 4^th International Symposium: "Trace Elements in Human - New Perspectives”, Athens, Greece, 2003
• 6^th Winter Research Conferences: "Oxidative Damage to DNA - protective effects of nutrition and drugs”, Les Houches, France, 2003
• 7^th Lublin Environmental Magnesium Conference: "Elements in Agriculture and Medicine”, Lublin, Poland, 2003
• 7^th Scientific Conference: "Health Effects of the Environmental Pollution”, Augustów, Poland, 2003
• 5^th International Scientific-Technical Conference: "Circulation of Elements in the Nature: Bioaccumulation – Toxicity – Counteraction - European Integration”, Warsaw, Poland, 2003

• 7^th International Symposium: "Zinc in the Environment – Ecological and Methodological Problems”, Warsaw, Poland, 2002
• 6^th Lublin Environmental Magnesium Conference, Lublin, Poland, 2002
• 11^th International Symposium: "Molecular and Physiological Aspects of Regulatory Processes of the Organism”, Krakow, Poland, 2002
• 8^th Scientific Symposium of the Polish Society of Toxicology, Lodz, Poland, 2002

• 6^th All-Polish Scientific Conference: "Xenobiotic Interactions”, Poznań, Poland, 2001
• 8^th International Symposium of the Polish Magnesium Society, Nałęczów, Poland, 2001
• 4^th International Scientific-Technical Conference: "Circulation of Elements in Nature, Bioaccumulation – Toxicity – Counteraction - European Integration”, Warsaw, Poland, 2001
• 7^th National Ecological Congress ECO-MED, Tarnów, Poland, 2001

• 3^rd Conference on Trace elements: "Effects on Organisms and Environment”, Sopot, Poland, 2000
• Scientific Conference: "Toxicological and Pharmacological Aspects of Xenobiotics Action”, Olsztyn, Poland, 2000
• 6^th National Ecological Congress ECO-MED: “Environmental Dangers for Community on the Threshold of XXI Century”, Tarnów, Poland, 2000

• 7^th International Symposium: "Molecular and Physiological Aspects of Regulatory Processes of the Organism", Krakow, Poland, 1998
• 2^nd International Symposium: „Trace  elements - effects on organisms and environment", Cieszyn, Poland, 1998
• 33^rd Conference of the Polish Histochemical and Cytochemical Society, Kazimierz Dolny, Poland, 1998

• 2^nd Domestic Symposium of Veterinary Immunologists: "Molecular Biology in the Protection of Human and Animal Health", Świnoujście, Poland, 1997
• 6^th International Symposium: "Molecular and Physiological Aspects of Regulatory Processes of the Organism", Krakow, Poland, 1997
• 33^rd Symposium of the Polish Biochemical Society, Katowice, Poland, 1997
• 2^nd International Scientific-Technical Conference: "Circulation of Elements in Nature: Bioaccumulation – Toxicity – Conteraction - European Integration", Warsaw, Poland, 1997
• 4^th Domestic Ecological Congress ECO-MED, Tarnów, Poland, 1997

• 5^th International Symposium: "Molecular and Physiological Aspects of Regulatory Processes of the Organism", Krakow, Poland, 1996
• Scientific Conference: "Metals and Metalloids – Farmacological, Toxicological and Environmental Aspects", Białowieża, Poland, 1996
• 6^th Scientific Conference of the Polish Society of Toxicology: "Toxicology and Civilization Dangers", Nałęczów, Poland, 1996

 

Selected presentations on foreign scientific conferences

2015 - China

• The research on the vanadium(V)-magnesium(Mg) interactions: an in vivo experimental model. 5^th International Symposium on Metallomics, September 9-12, Beijing

2014 – Italy

• The effect of vanadium and magnesium administration on rat femoral bone micromorphology. 9^th International Vanadium Symposium: Chemistry, Biological Chemistry & Toxicology (V9), June 29 – July 2, Padova

2012 – USA

• Inhibitory and stimulating effect of magnesium on vanadate-induced lipid peroxidation in in vitro conditions. 8^th International Vanadium Symposium: Chemistry, Biological Chemistry & Toxicology (V8), August 15-18, Washington DC

2007 – Spain

• The effect of vanadium and/or magnesium on lipid peroxidation in liver and kidney of rats. 3^rd International Symposium FESTEM (Federation of European Societies on Trace Elements and Minerals), May 16-19, Santiago de Compostela

2005 – Greece

• The effect of vanadium(V) and/or chromium (III) on lipid peroxidation in the liver and kidney of rats. 5^th International Symposium: “Trace Elements in Human - New Perspectives”, October 13-15, Athens

2004 – Germany

• Some selected parameters of the antioxidative system in rats treated with vanadium or/and chromium. 3^rd International Symposium: “Trace Elements and Minerals in Medicine and Biology”, May 13-15, Munich

2003 – Greece

• Total antioxidant status in plasma of rats in vanadium-chromium interaction. 4^th International Symposium: “Trace Elements in Human - New Perspectives”, September 9-11, Athens

 

Selected conference announcements (2012-2022)

• Ścibior A., Adamczyk A., Niedźwiecka I., Gołębiowska D., Fornal E. 2012. Influence of the 12-week vanadate and magnesium co-administration on the concentration of selected elements in the femur of rats. 9^th International Symposium: "Trace Elements in the Environment”, Olsztyn, Book of Abstracts, pp.: 137-138.
• Ścibior A., Gołębiowska D., Niedźwiecka I. 2013. The level of selected macro- and microelements in the plasma of rats following chronic vanadium and magnesium administration [published in Polish: Poziom wybranych makro- i mikroelementów w osoczu krwi szczurów w następstwie przewlekłego podawania wanadu i magnezu]. 16^th Scientific Lublin Magnesium Conference: "Chemical Elements and Health”, Lublin, Book of Abstracts, pp.: 125.
• Ścibior A., Gołębiowska D., Niedźwiecka I. 2013. Selected biochemical blood parameters in rats following administration vanadium and magnesium separately and in combination [published in Polish: Wybrane parametry biochemiczne krwi szczurów w następstwie podawania wanadu i magnezu oddzielnie oraz w kombinacji]. 16^th Scientific Lublin Magnesium Conference: "Chemical Elements and Health”, Lublin, Book of Abstracts, pp.: 126.
• Ścibior A., Gołębiowska D. 2014. Magnesium-induced cerebral lipid peroxidation. 17^th Scientific Lublin Magnesium Conference: "Chemical Elements and the Quality of Life”, Lublin, Book of Abstracts, pp.: 149.
• Ścibior A., Gołębiowska D. 2014. Effect of 18-week administration of vanadate separately or in combination with magnesium on lipid peroxidation in the brain of rats. 17^th Scientific Lublin Magnesium Conference: "Chemical Elements and the Quality of Life”, Lublin, Book of Abstracts, pp.: 150.
• Ścibior A., Gołębiowska D. 2014. Influence of vanadate and magnesium on cerebral lipid peroxidation under in vitro conditions. Scientific Conference of the Polish Society of Toxicology: "Human, Food, Environment – problems of modern toxicology”, Olsztyn, Book of Abstracts, pp.: 117.
• Ścibior A. 2015. Influence of 18-week treatment with vanadium (V) and magnesium (Mg) on the total antioxidant status in the plasma and in some internal organs of rats. 18^th Scientific Lublin Magnesium Conference: „The role of elements in the biosphere”, Lublin, Book of Abstracts, pp.: 140. 
• Ścibior A., Gołębiowska D., Niedźwiecka I.  2015. Effects of 18-week administration of vanadium (V) and magnesium (Mg) in rats: The L-ascorbic acid level in some internal organs and urinary excretion. 18^th Scientific Lublin Magnesium Conference: „The role of elements in the biosphere”, Lublin, Book of Abstracts, pp.: 141. 
• Ścibior A., Adamczyk A., Gołębiowska D., Niedźwiecka I.  2015. The level of some elements in rats' erythrocytes in the conditions of vanadium (V) and/or magnesium (Mg) administration. 18^th Scientific Lublin Magnesium Conference: „The role of elements in the biosphere”, Lublin, Book of Abstracts, pp.: 142. 
• Ścibior A., Gołębiowska D.  2015. Urinary excretion of some micro- and macro-elements in the conditions of 18-week administration of vanadium (V) and/or magnesium (Mg) in rats. 18^th Scientific Lublin Magnesium Conference: „The role of elements in the biosphere”, Lublin, Book of Abstracts, pp.: 143. 
• Ścibior A., Gołębiowska D., 2016. Evaluation of changes in selected markers of oxidative stress in bone of rats receiving vanadium and magnesium separately and in combination [published in Polish: Ocena zmian wybranych markerów stresu oksydacyjnego w kościach szczurów otrzymujących wanad i magnez oddzielnie oraz w kombinacji]. 19^th Scientific Lublin Magnesium Conference: "The significance of elements in the environment and medicine”, Lublin, Book of Abstracts, pp.: 107.
• Ścibior A., Gołębiowska D., 2016. The level of glutathione and the activity of GSH-dependent enzymes in bone of rats receiving vanadium and magnesium separately and in combination [published in Polish: Poziom glutationu i ocena aktywności GSH-zależnych eznymów w kościach szczurów otrzymujących wanad i magnez oddzielnie oraz w kombinacji]. 19^th Scientific Lublin Magnesium Conference: "The significance of elements in the environment and medicine”, Lublin, Book of Abstracts, pp.: 108.
• Ścibior A., Gołębiowska D., 2016. The effect of vanadium and magnesium on the concentration of transferrin receptor 2 (TfR2) in the liver of rats [published in Polish: Wpływ wanadu i magnezu na stężenie receptora transferynowego 2 (TfR2) w wątrobie szczurów]. 19^th Scientific Lublin Magnesium Conference: "The significance of elements in the environment and medicine”, Lublin, Book of Abstracts, pp.: 109.
• Ścibior A., Gołębiowska D., 2016. The effect of vanadium and magnesium on the concentration of ferroportin (FPN1) in the liver of rats [published in Polish: Wpływ wanadu i magnezu na stężenie ferroportyny (FPN1) w wątrobie szczurów]. 19^th Scientific Lublin Magnesium Conference: "The significance of elements in the environment and medicine”, Lublin, Book of Abstracts, pp.: 110.
• Ścibior A., Staniszewska M., Sadok I., Gołębiowska D., Kurus J. 2017. Application of the high performance liquid chromatography for determination of L-ascorbic acid in the liver of rats chronically exposed to vanadium during magnesium supplementation. 5^th All-Polish Scientific Conference: "Animals in scientific research", Warsaw, Book of Abstracts, pp.: 160.
• Ścibior A., Staniszewska M., Sadok I., Gołębiowska D., Kurus J. 2017. The level of L-ascorbic acid in the bone of rats receiving vanadium and magnesium separately and in combination. 12^th Training and Scientific Conference of the Polish Society of Toxicology: "Different faces of toxicology", Pulawy, Book of Abstracts, pp.: 100.
• Ścibior A., Kurus J., Gołębiowska D.  2018. Evaluation of the alkaline phosphatase activity in bone of rats chronically exposed to vanadium during magnesium administration. 21^st Scientific Lublin Magnesium Conference: "Elements in the environment and medicine”, Lublin, Book of Abstracts, pp.: 76.
• Ścibior A., Hus I., Mańko J., Jawniak Dariusz. 2019. The effect of vanadium and magnesium on the level of hepcidin (HEPC), hemojuvelin (HJV) and transferrin receptor 1 (TfR1) in the rat liver. 22^nd Scientific Lublin Magnesium Conference: "Elements - from the environment to medicine”, Lublin, Book of Abstracts, pp.: 25.
• Ścibior A., Pietrzyk Ł., Plewa Z., Skiba A. 2019. Vanadium - an element with a significant biological role, a wide range of applications, and pharmacological potential. 6^th Scientific Conference "Animals in scientific research", Abstracts, pp.: 142-143.
• Ścibior A., Brzoska M.M., Roszczenko A. 2022. The influence of vanadate and/or magnesium on bone mineral density and biomechanical properties of the femur and tibia in male rats. XVI International Magnesium Symposium: “Magnesium in Health and Disease” (online virtual meeting). Abstracts.
• Ścibior A. 2022. Vanadium and neurodegenerative diseases - promising therapeutic effects: animal model. 7^th Scientific Conference "Animals in scientific research", Abstracts.

Participation in conferences/workshops/seminars referring to in vivo /  in vitro studies

• scientific symposium: ”Laboratory Animals in Breeding and in Experiments”, Tri-Cit Central Animal Laboratory + Research and Service Centre of Medical University of Gdańsk, Poland, 2006
• training course for persons supervising the animal experiments, Pulawy, Poland, 2007
• training course in filling out of applications to the Local Ethical Committees on Animal Testing, Warsaw University of Life Science, Poland, 2011
• workshop: "Diverse use of DSI telemetry systems” organized within the framework of the 3^rd All-Polish Conference entitled “Animals in Scientific Studies”, Warsaw University of Life Science, Poland, 2013
• workshop: "Registration system for the animal room” organized within the framework of the 3^rd All-Polish Conference entitled “Animals in Scientific Studies”, Warsaw University of Life Science, Poland, 2013
• training course: “Higher efficiency, standardization, acceleration of the in vivo and in vitro studies”, Medical University, Warsaw, Poland, 2013
• scientific seminar: ”Modern techniques of experiments performed on animals” linked with a presentation of new experimental animal facility of the Jagiellonian University organized by Polish Laboratory Animal Science Association (PolLASA) and Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, 2014
• training course: "Behavioral and physiological studies: Zebrafish, rodents and large laboratory animals", Lublin, 2015

Editorial experience

August 2014 - present

Editorial Board Member of Edorium Journal of Cell Biology

April 2016 - present

Editorial Board Member of Peertechz Journal of Environmental Science and Toxicology

 

Reviewer for several peer-reviewed international scientific journals

• included in the JCR database
• not included in the JCR database

Organising activity

2009 - 2015

Investigator in the Project entitled: "Bulding and equipping the Centre for Interdisciplinary Research" realized within the framework of the Operational Programme "Development of Eastern Poland" 2007-2013, Priority I: Modern Economy, Action 1.3. The Advancement of Innovation, co-financed by the European Regional Development Fund (POPW.01.03.00-06-003/09-03; PORPW 1.3., PARP)

February 2010 - 2015

Head of organization of the Laboratory of Oxidative Stress, Centre for Interdisciplinary Research

January 2014 - 2015

Member of the planning team on realization and introduction of the Project entitled ”Building and equipping the Centre for Interdisciplinary Research” within the framework of substantive assignments concerning the Laboratory of Oxidative Stress

2014

Author of a report on the modernization of a vivarium for the Laboratory of Oxidative Stress 

 

Awards

2003

• The third-degree individual award of the Rector of the Catholic University of Lublin for original scientific papers in the field of biology and for the excellent didactic and educative work

2006

• The second-degree individual award of the Rector of the John Paul II Catholic University of Lublin for four scientific papers published in journals included in the Philadelphia List and for the 3rd Lublin Festival of Science

2007

• The third-degree team award of the Rector of the John Paul II Catholic University of Lublin for achievement of the highest number of points of the Ministry of Higher Education from among all the scientific workers of the Faculty of Mathematics and Natural Sciences

2009

• The fourth-degree team award of the Rector of the John Paul II Catholic University of Lublin for original and creative scientific achievments documented by scientific papers and for educating scientific staff
• The first-degree team award of the Rector of the John Paul II Catholic University of Lublin for creative involvement in a work on realization of a project - Centre for Interdisciplinary Research

2015

• The third-degree individual award of the Rector of the John Paul II Catholic University of Lublin for original and creative scientific achievments
• Metallomics Poster Award, The 5th International Symposium on Metallomics (Beijing, China) http://blogs.rsc.org/mt/2015/09/18/prize-winners-5th-international-symposium-on-metallomics/

2020

• The second-degree individual award of the Rector of the John Paul II Catholic University of Lublin for original and creative scientific achievments

2022

• The second-degree individual award of the Rector of the John Paul II Catholic University of Lublin for original and creative scientific achievments

State Awards

2022

The Silver Medal for Long Service

Membership in international organizations and scientific societies

2015-2017

Member of the American Chemical Society (ACS)

2015-2018

Member of the Royal Society of Chemistry (RSC)

Membership in national organizations and scientific societies

since September 2011

Member of the Polish Laboratory Animal Science Association (PolLASA, incorporated into the Federation of European Laboratory Animal Science Associations, FELASA)

since June 2014

Member of the Polish Society of Toxicology

2014-2017

Member of the Polish Society of Laboratory Diagnostics

since April 2015

Member of the Polish Magnesiological Society

Editorial board

since June 2023

Member of the Topical Advisory Panel for International Journal of Molecular Sciences section Molecular Toxicology

RESEARCH AREA 

Keywords

(a) in vitro experimental model: cultured primary astrocytes, vanadium, cytotoxicity, oxidative stress

(b) in vivo experimental model: vanadium, magnesium, bioelements, metal interactions, mechanisms of toxicity, oxidative stress, biomarkers, tissues, mineral status, experimental toxicology, clinical chemistry

Research interests

Scientific activity includes:

• mechanisms of toxicity of selected elements
• consequences, character, and mechanisms of metal interactions
• bone micromorphology at the exposure to some metals / analysis of the chemical composition of bone with the X-ray photoelectron spectroscopy (XPS) in cooperation with Laboratory of X-Ray Optics http://www.kul.pl/laboratory-of-x-ray-optics,26887.html
• seeking the most sensitive biomarkers to assess organism reactions to some metals
• cytotoxicity of selected elements (in vitro model)

Graphical Abstracts of selected papers

Foreign cooperation 

• University of Granada, Spain

National cooperation 

• University of Information Technology and Management in Rzeszow, Collegium Medicum, Department of Lifestyle Disorders and Regenerative Medicine, 
• Medical University of Lublin (Clinic of Haematooncology and Bone Marrow Transplantation; Department of Didactics and Medical Simulation)
• 1 Military Clinical Hospital with the Outpatient Clinic in Lublin, Department of General, Oncological, and Minimally Invasive Surgery
• Maria Curie-Skłodowska University in Lublin, Institute of Biological Sciences
• Medical University of Bialystok, Faculty of Pharmacy with the Division of Laboratory Medicine
• Medical University in Warsaw
• Cardinal Stefan Wyszyński University, Collegium Medicum, Department of Biochemistry and Laboratory Diagnostic
• Medical University of Silesia, Faculty of Medical Sciences in Zabrze
• Humanitas University in Sosnowiec, Psychology Institute 

Techniques/methods

Microwave digestion, Atomic Absorption Spectrometry (AAS), UV-Vis Spectrophotometry, Flow cytometry, Microscopy, Potentiometry, ELISA Immunoenzymatic method

Laboratory of Oxidative Stress is equipped with:

• ADVIA 2120i Haematology system with veterinary software (Siemens)
• Flow cytometer: MACSQuant Analyzer 10 (Miltenyi Biotec)
• Automated EasyLyte Na/K/Cl Analyzer (Medica)
• Automated XL-640 Veterinary Analyzer (ERBA Diagnostics Mannheim GmbH)
• Automated BS-120 Biochemistry Analyzer (Mindray)
• Laura Smart urine analyzer (ERBA Lachema)
• U-2900 Double Beam Spectrophotometer (Hitachi) with 2J1-0104 Temp Controller ED-5 (Hitachi) and Heating Circulator with Open Bath (Julabo)

 

• Speedwave Four Microwave Digestion System with a 12-position rotor; temperature and pressure monitoring using a contact-free sensor in each vessel with the control of the course and reading (Berghof)
• Z-2000 Atomic Absorption Spectrometer with two atomizers (Flame and Graphite Furnace Atomization) (Hitachi)

 

• Synergy 2 Multi-Mode Microplate Reader (BioTek) equipped with the following detection modes: UV-visible Absorbance, Fluorescence, Luminescence, and Fluorescence polarization
• ELx50 Microplate Strip Washer (BioTek)
• DTS-4 digital thermostatic micro plate shaker (Elmi Laboratory Equipment)

 

• IX73 Inverted Microscope (Olympus) with the CellSens Imaging Software 
• HERAsafe KS 12 Laminar Flow Cabinet (Thermo Electron LED GmbH)
• Heracell 150i CO₂ Incubator with copper chamber (Thermo Fisher Scientific)

 

• BioGen PRO200 Homogenizer (PRO Scientific Inc.)
• UP 50H Compact Ultrasonic Homogenizer (Hielscher Ultrasonics GmbH)

 

Other laboratory equipment:

• SH 12/24 hematological adder
• XA 100 3Y.A analytical balance (Radwag)
• PS 210 R.2 and PS 2500 3.Y precision balances (Radwag)
• Heraeus Megafuge 11R Refrigerated Centrifuge (Thermo Fisher Scientific)
• HLP Spring 5R water system (Hydrolab)
• Haake DC10-P5/U Heating Circulator with Open Bath (Thermo Fisher Scientific)
• HeraFreeze HFU 486 Basic (Thermo Fisher Scientific)
• LCv 4010 Freeze-Refrigerator (Liebherr)
• TC240 Thermocenter Oven (SlavisLab)
• Shaking WNB 14 water bath (Memmert)
• ONE 45 oil bath (Memmert)
• Polwater DL-100 V 717 Demineralizer (Labopol)
• DEM-20 Distiller
• Computer with Graphic Design Software (CorelDRAW Graphics Suite X6 PL Win Box)